Tuesday 29 December 2015

Bone marrow biopsy today

Lauren's in for a bone marrow biopsy (RAH - ADL) this morning - to see what's happened with her blast counts (leukaemic cells) from this last cycle of inotuzumab completed before Christmas. Hopefully it's brought her blast count down from the 39% it was in Melbourne when she 'qualified' for the trial by having at least a 5% blast count. We'll find out results with MRD reading later this week or early next week. The plan is she goes for tests in Melbourne on Jan 11 and we go for the transfusion of her T-Cells (genetically modified) on 20 Jan and transfusion planned for Jan 28 or 29 - can't remember which).

Her T-cells are in Philadelphia (I think) now and being modified today (Jan 29) in the laboratory. Then they'll reproduce these genetically modified T-Cells and the plan is for her to have these infused late January 2016 in Melbourne. Encouraged by the latest paper showing results of this new treatment, but at end of day 1% or 99% doesn't mean much until you know your daughter will live or not. Whilst I'm quietly confident it will work, I know this is the last roll of the dice under current treatment regimes currently being trialled. Hopefully those thousands of paper cranes and their associated wishes continue to work wonders!!!

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